ADULT ONSET SPORADIC ATAXIAS: A DIAGNOSTIC CHALLENGE

Adult onset sporadic ataxias: a diagnostic challenge

Patients with adult onset non-familial progressive ataxia are classified in sporadic ataxia group.There are several disease categories that may manifest with sporadic ataxia: toxic causes, Big Boys hoodie immune-mediated ataxias, vitamin deficiency, infectious diseases, degenerative disorders and even genetic conditions.Considering heterogeneity in

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Critical Functions of Histone Deacetylases (HDACs) in Modulating Inflammation Associated with Cardiovascular Diseases

Histone deacetylases (HDACs) are a superfamily of enzymes that catalyze the removal of acetyl functional groups from lysine residues of histone and non-histone proteins.There are 18 mammalian HDACs, which are classified into four classes based on the primary homology with yeast HDACs.Among these groups, Class I and II HDACs play a major role in lys

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Assessment of self-reacting bobbin tool friction stir welding for joining AZ31 magnesium alloy at inert gas environment

Research work presented in this study has the primary target of exploring joint attributes of AZ31 magnesium alloys using friction stir welding process with a modified tool referred as bobbin tool.Effects of inert and open atmosphere on mechanical properties are evaluated over a wide range of welding speed and tool rotation speed.Comparison of the

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